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Customs Clearance of Lysine and Its Esters in Iran (HS Code + Documents, Permits & Requirements)

Lysine is an essential amino acid and a key component of proteins that is not synthesized in humans or animals and must be supplied through diet. Given its nutritional role and industrial/pharmaceutical applications, customs clearance of lysine and its esters involves health, veterinary, and standards sensitivities and requires choosing the correct tariff line (HS), preparing complete documentation, and coordinating with the competent authorities.

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1) Key Applications of Lysine and Its Esters

Animal Feed
Lysine is one of the most important essential amino acids in livestock and poultry nutrition and is widely used as a growth-promoting supplement. Adding lysine to rations improves muscle growth, increases feed conversion ratio (FCR), strengthens the immune system, and reduces mortality.
It also plays an effective role in optimizing ration formulation and prevents waste of protein resources. In broilers, layers, and fattening livestock, adjusting the lysine-to-methionine ratio is a key factor for achieving high performance.

Nutritional & Pharmaceutical Supplements
Beyond veterinary use, lysine is used in the production of human dietary supplements. It helps tissue repair, improves calcium absorption, boosts the immune system, and supports nitrogen balance in the body.
In veterinary applications, lysine-containing supplements are used to increase appetite, improve growth, and enhance the general condition of young or convalescent animals. Combining it with vitamin C or zinc can further improve absorption and efficacy.

Food Industry
In food processing, lysine is used as a protein-enrichment factor in various products such as energy drinks, flour products, infant formula, and baby food.
Adding lysine increases nutritional value, improves protein quality, and supplies essential amino acids.
Lysine is also used in producing certain amino-based additives and flavorings.

Lysine Esters in Pharmaceuticals
In the pharmaceutical industry, lysine derivatives and esters play a major role in enhancing absorption, stability, and efficacy of active ingredients. For example, lysine esters are used in the formulation of anti-inflammatory drugs, antivirals, and tissue-regeneration supplements.
These compounds help control drug release and improve bioavailability, and they are gaining attention in next-generation medicines.

2) Customs Tariff (HS Code) for Lysine and Its Esters

Selecting the correct tariff line is critical to prevent valuation disputes and speed up formalities. According to international classification:

Commodity Short Description HS Code
Lysine and its esters; salts Essential amino acid; feed/food/pharma 29224100

Under 29224100, lysine and its esters (and salts) are classified. For more complex derivatives, other headings in Chapter 29 may apply depending on functional groups/precise formula; the final determination is based on the COA and datasheet.

3) Special Import & Export Conditions

Health/Veterinary/Standards Permits: Depending on end use, permits are required from the Veterinary Organization, Food and Drug Organization (Ministry of Health), and the National Standards Organization.

Labeling & Quality Documents: SDS, Certificate of Analysis (COA), and batch/lot information must fully match transport/commercial documents.

Common Countries of Origin: China, Germany, the Netherlands, and the United States are major global suppliers.

Exports from Iran: Currently limited; domestic demand (especially feed for livestock/poultry) is primarily met through imports.

4) Import/Export Volumes

Iran imports several thousand tons of lysine annually for livestock/poultry feed and certain food/pharma uses. Globally, lysine production and trade capacity is largely concentrated among Asian and European producers, with China having a prominent share.

5) Major Exporters & Importers

Key exporters: China (largest producer), Germany, the Netherlands, and the United States.

Major importers: Iran, Brazil, Russia, and India (due to the scale of their livestock and feed industries).

6) Documents Required for Clearance

 Commercial Invoice (CI)

The commercial invoice is one of the basic documents in the import process and includes a full description of the goods, tariff code (HS Code), FOB or CIF value, payment terms, and buyer/seller details. It is the primary basis for calculating customs duties and must fully match the order registration and the customs declaration.

 Bill of Lading (B/L) or Air Waybill (AWB)

The bill of lading is the title document for international carriage and includes the shipper, consignee, vessel/flight, number of packages, gross weight, ports of loading and discharge, and carriage terms.
For clearance, the B/L contents must be reconciled with the Packing List and the Commercial Invoice this is a core requirement for customs examiners.

 Certificate of Origin (CO)

The CO is issued by the chamber of commerce in the exporting country and shows in which country the goods were actually produced or assembled.
It is decisive for preferential tariffs, use of trade agreements, and verifying origin.

 Packing List

This lists the exact number of cartons or pallets, each package’s net and gross weight, dimensions, packaging type, and shipping marks.
During physical inspection, customs officers reconcile the packing list with the actual shipment.

 Certificate of Analysis (COA)

Usually issued by the manufacturer or an accredited laboratory, the COA states technical specifications such as purity percentage, moisture, heavy metals, microbiological attributes, and chemical parameters.
It is mandatory for chemical, food, pharmaceutical, and cosmetic raw materials.

 Health or Veterinary Certificate

For items related to animal feed, foodstuffs, dairy, meat, and other animal/plant products, a health or veterinary certificate from the country of origin is required. This certifies compliance with international sanitary standards.

 Food and Drug Organization (FDA/IFDA) Permit

For items used in pharmaceuticals, dietary supplements, essences, and specific chemical esters, an authorization from the food and drug authority is required.
This shows official approval for human/pharmaceutical use in the destination country.

 Customs Declaration

The customs declaration is an official document submitted by the importer or broker and includes full details of value, quantity, tariff (HS Code), country of origin, transport details, and commercial documents.
It forms the basis for assessing import duties, VAT, and legal permits.

Order Registration in the National Trade Single Window (NTSW)

The final—and one of the most important—steps is registering the order in Iran’s NTSW. Without a valid registration code, official clearance is not possible.
At this stage, all product details (HS Code, weight, value, country of origin, payment and shipment terms) must be entered precisely so that the import permit is issued.

Need exact HS determination, health/veterinary permits, and document prep? Our team manages end-to-end lysine and ester cases.

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FAQs

What is the HS Code for lysine and its esters?

Lysine and its esters (and salts) are classified under 29224100. For special derivatives with additional functional groups, other headings in Chapter 29 may apply based on exact structure.

Which permits are required to import lysine?

Depending on end use: Veterinary Organization, Food and Drug Organization (Ministry of Health), and National Standards Organization. For pharmaceutical esters, a specialized permit from the Food and Drug Organization is mandatory.

What are common import origins and the export status of lysine in Iran?

Imports mainly come from China, Germany, the Netherlands, and the United States. Exports from Iran are currently limited, and domestic demand is largely met through imports.

    Special Customs Services by Saba Brokerage

    Specialized customs consulting: Risk analysis and correct tariff classification to minimize costs.
    Permit acquisition: Veterinary, food & drug, standards, and health according to end use.
    Professional handling of formalities: From order registration to examination and final release.
    Time/cost optimization: Reducing dwell time and unnecessary expenses.
    Contact our experts to coordinate.

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